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Twilite Three Specifications

Sensor head
Dimensions 80 x 62 x 56 mm (L x W x H). Approx. 6 kg
Material machined from solid Inermet (TM) tungsten
Scintillator LYSO Connection via two flexible light guides, standard length 2 m, up to 10 m upon request, 5+8 m for PET/MR with optical coupler


Sensitivity catheter ID 0.28 mm: 0.2 cps/kBq/ml (mouse)
catheter ID 0.58 mm: 0.8 cps/kBq/ml (rats)
catheter ID 1.00 mm: 2.4 cps/kBq/ml (human)
Linearity Full linearity up to 6000 cps,
deviation at 10000 cps: < 1 %


Photon detection device
Portable case containing photon counting device and acquisition electronics
Stand-alone operation possible for system check, calibration etc.
Touch screen with device status and current count values [cps]


Data acquisition
Software PMOD, PSAMPLE module
System requirements: 64-bit OS (Windows 10, 8, 7, MacOSX, Linux), 4GB RAM
Sampling frequency 1 kHz maximum
Interface TCP/IP (wireless optional)

¬ęThe developers of Swisstrace have long-standing experience in molecular imaging using radiotracers. The design of the systems is optimized for medicine and research using positron emission tomography¬Ľ

The core of the twilite three system is a very compact measuring head machined from medical grade tungsten, which shields the LYSO crystals from outside radiation and is fully MR compatible. The scintillations are conveyed to the photon detection unit via two flexible high efficieny light guides. This elegant design is without any electronics in the sensor head and thus avoids any potential problems of electromagnetic interference with other devices. Furthermore, this design minimizes any potential risks in human research experiments.

Data acquisition is performed with the dedicated PMOD module PSAMPLE via a TCP/IP interface. A touch-screen on the front-panel serves as the user interface, and also displays the current status and measured values. The twilite three's performance is outstanding. The system shows excellent sensitivity, linearity and signal-to-noise, also in the presence of high external radiation.

Since its introduction, the twilite and twilite two have been installed at sites in Europe, North/South America, Canada, Asia and Australia. In addition to clinical and preclinical PET and PET/CT sites, more and more sites equipped with PET/MR scanners are using the system for the acquisition of arterial input curves.


Alfred Buck, MD, MSc

CEO Swisstrace


Professor Emeritus of Nuclear Medicine PET Center
University Hospital Zurich


Bruno Weber, PhD



Professor of Experimental Imaging Institute of Pharmacology and Toxicology
University of Zurich


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swisstrace GmbH
Alte Landstrasse 8
6313 Menzingen

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